If you're not staying on a houseboat - you have not experienced Amsterdam.
Canals
The canals are maybe what most people think of when they think of Amsterdam. And strolling along a canal. in the month of May truly is a wonderful experience, unless it's raining :)
Houseboats
Speaking of canals, the houseboats on those canals are something you should experience first hand a least once in your life. So why not rent one for your vacation.
Museums
From The Rijksmuseum with Rembrandts to the Museum of Sex... what all the sex? You kind fin anything that tickles your mind in Amsterdam.
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